Background: Congenital hearing loss is remarkably heterogeneous, with over 130 deafness genes and thousands of variants, making for innumerable genotype/phenotype combinations.Understanding both the pathophysiology of hearing loss and molecular site of lesion along the auditory pathway permits for significantly individualized counseling.Electrophys
The segmental pattern of the vertebrate body is established via the periodic formation of somites from the Toasters presomitic mesoderm (PSM).This periodical process is controlled by the cyclic and synchronized activation of Notch signaling in the PSM.Protein O-fucosyltransferase1 (Pofut1), which transfers O-fucose to the EGF domains of the Notch1
We describe the case Toasters of a 69-year-old woman who presented with submassive pulmonary embolism without overt shock, but with significant signs of right ventricular failure and dyspnea on minimal exertion.She was managed using a point-of-care ultrasound and pulmonary artery pressure-guided approach in order to minimize total thrombolytic Obso
Globally, energy standards for new buildings are being reinforced to improve energy efficiency, and remodeling policies are being promoted for old buildings.The South Korean Government is promoting green remodeling projects, and focusing on research and product development to improve the performance of old windows and curtain walls.In line with Bev